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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Viral Vector Stable Cell Line Development Lead where you will be the subject matter expert overseeing all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation. You will leverage your expertise to establish GMP-ready stable Viral Vector producer cell lines, from concept initiation to delivering top-performing clones for Takeda’s Cell Therapy pipeline. A key responsibility will be to manage cross-functional collaborations across CMC, Strategy, and Research teams to ensure timely delivery of robust stable producer clones for Takeda’s pipeline.

How you will contribute:

• Serve as the subject matter expert and lead for all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation.

• Partner with the Viral vector strategy team for the development and execution of strategy for generation of stable Viral vector producer cell lines for Gamma Retrovirus for various Cell Therapy programs.

• Work in close collaboration with Upstream & Downstream Viral Vector Process development teams to design, develop and optimize robust viral production processes for stable producer cell lines.

• Apply your expertise in genomics, transcriptomics and analytical assays such as Viral Vector titration assay, DNA sequencing, PCR, Southern/Northern blots, in collaboration with the Analytical Development team for comprehensive cell line characterization and optimization.

• Ensure compliance with regulatory requirements and guidelines for stable cell line development and viral vector production, maintaining adherence to industry standards.

• Leverage your proven experience in establishing and maintaining cell banks (RCB, MCB, WCB) to support consistent and reliable cell line development.

• Utilize your familiarity with automated systems to conduct high-throughput screening of cell lines and optimize experimental conditions.

• Ensure optimal alignment and coordination with cross-functional matrixed teams.

• Work closely with senior team leaders and cross-functional teams and provide scientific leadership and technical recommendations.

• Support IND enabling studies and filing related document preparation. Draft technical documents, such as SOPs and study reports.

• Lead cross-functional teams effectively, driving collaboration across disciplines and delivering high-quality results to advance Takeda’s Cell Therapy pipeline.

• Collaborate with data and digital teams to develop fully digitalized data capture and tracking.

• Serves as a technical mentor for junior staff, providing guidance and training in laboratory technology and leverages domain expertise to support their development and enhance functional capabilities.

• Preparation and presentation comprehensive technical or project reports and formal presentations to both internal and external audiences.

Minimum Requirements/Qualifications:

• PhD degree in a scientific discipline with 3+ years experience or MS with 8+ years experience, or BS with 10+ years experience in Virology, Molecular biology, Immunology, Bioengineering, or related scientific disciplines with relevant experience.

• 3+ years of industry experience in Cell line development is required.

• Previous experience in Cell Therapy or related field is highly preferred.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

133,000.00 - 209,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes