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Job Information
Beth Israel Lahey Health Research Associate in Boston, Massachusetts
Job Type: Regular
Time Type: Full time
Work Shift: Day (United States of America)
FLSA Status: Non-Exempt
When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives.
This position is a terrific opportunity for a person trained in lipid Mass Spectrometry to lead a project with high relevance to human diabetes. The Kahn lab studies the molecular and cellular mechanisms underlying Type 1 diabetes, Type 2 diabetes, and obesity. Our work has had a major impact on understanding the critical role of the adipocyte as an endocrine organ and as a metabolic “factory” consuming and producing metabolites that have systemic effects on insulin action, energy balance, insulin secretion and inflammation. The lab uses liquid chromatography Mass Spectrometry, metabolomics, molecular biology, mouse genetics, and transcriptional profiling with validation by gene overexpression and knockdown to discover new mechanisms for the regulation of metabolism and immune responses.
Specific Job Responsibilities
Carries out detailed LC-MS analyses of lipids in biological samples including precise measurements of specific lipids in a human biomarker study.
Operates and maintains one or two LC-mass spectrometers (triple quadrupole) for small molecule separation, identification and quantification.
Prepares samples for lipid profiling studies from tissues, biofluids and cells using a variety of sample preparation techniques (e.g. liquid-liquid extraction, SPE).
May help to produce and isolate samples using cell culture techniques and subcellular fractionation methods.
Helps ensure that lab supplies, reagents, instrument spare parts, software, etc. are in place in accordance with project requirements.
Consults scientific literature and collaborates with other researchers from the scientific community as needed.
Tracks and compiles results and presents them in lab meeting. Performs standard statistical analyses.
Prepares detailed technical documents describing procedures and results.
Job Description:
Essential Responsibilities:
Functions as a principal technical specialist for a research laboratory or for a specific research project. Functions as an internal consultant and as a resource to other labs both internally and externally. Performs and devises specialized tests and research procedures, troubleshooting problems of own and other researchers' results.
Conducts broad range of experiments involving advanced technology. Participates in the design of experimental protocols to achieve the objective of the research project.
May prioritize work and assign work to lower-level technical personnel. May instruct laboratory techniques and methodology to students and other research personnel. May be involved in complex data analysis and interpretation of results.
Collaborates with supervisor in writing and editing materials for publication. May assist in preparing manuscripts and writing abstracts. May write portion(s) of grant application, e.g.: Materials and Methods, or Experimental Design.
May present papers at society meetings. Attends conferences and courses, consults with other researchers and participates in professional activities to keep abreast of the latest technological developments as they relate to the research. Evaluates the applicability of these new developments and implements their use in collaboration with the principal collaborator.
Required Qualifications:
Bachelor's degree in Life Sciences or related field required. Master's degree preferred.
3-5 years related work experience required.
Bachelor's degree and four years experience. Or, a Master's degree and two years experience.
At least 2 years of experience performing Mass Spectrometry and ability to trouble-shoot problems with Mass Spec protocols.
Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases.
Competencies:
Decision Making: Ability to make decisions that are guided by general instructions and practices requiring some interpretation. May make recommendations for solving problems of moderate complexity and importance.
Problem Solving: Ability to address problems that are varied, requiring analysis or interpretation of the situation using direct observation, knowledge and skills based on general precedents.
Independence of Action: Ability to follow precedents and procedures. May set priorities and organize work within general guidelines. Seeks assistance when confronted with difficult and/or unpredictable situations. Work progress is monitored by supervisor/manager.
Written Communications: Ability to communicate clearly and effectively in written English with internal and external customers.
Oral Communications: Ability to comprehend and converse in English to communicate effectively with medical center staff, patients, families and external customers.
Knowledge: Ability to demonstrate full working knowledge of standard concepts, practices, procedures and policies with the ability to use them in varied situations.
Team Work: Ability to work collaboratively in small teams to improve the operations of immediate work group by offering ideas, identifying issues, and respecting team members.
Customer Service: Ability to provide a high level of customer service to patients, visitors, staff and external customers in a professional, service-oriented, respectful manner using skills in active listening and problem solving. Ability to remain calm in stressful situations.
Physical Nature of the Job:
Medium work: Exerting up to 50 pounds of force occasionally and or up to 20 pounds of force frequently. Job is physical in nature and employee needs to stand and/or move around through the majority of their shift.
As a health care organization, we have a responsibility to do everything in our power to care for and protect our patients, our colleagues and our communities. Beth Israel Lahey Health requires that all staff be vaccinated against influenza (flu) and COVID-19 as a condition of employment. Learn more (https://www.bilh.org/newsroom/bilh-to-require-covid-19-influenza-vaccines-for-all-clinicians-staff-by-oct-31) about this requirement.
More than 35,000 people working together. Nurses, doctors, technicians, therapists, researchers, teachers and more, making a difference in patients' lives. Your skill and compassion can make us even stronger.
Equal Opportunity Employer/Veterans/Disabled
Beth Israel Lahey Health
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