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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Scientist – In Vitro Neurobiology

The Neuroscience team at Eli Lilly is seeking an innovative and motivated Principal Scientist, with deep experience in cellular and molecular neurobiology, to contribute to the design and development of cell-based assays for target validation, compound characterization, and probing disease mechanisms. A successful candidate will work independently and cross-functionally with various teams to perform benchwork that supports discovery efforts and contribute to IND-enabling studies. The scope of work includes the design, execution, and analysis of in vitro and ex vivo experiments using human iPSC-derived cell models and rodent primary culture. The successful candidate will be self-motivated, creative, and organized, with a desire to succeed at the highest level in a highly collaborative and fast-paced environment.

Job Responsibilities:

• Execute in vitro and ex vivo pharmacology evaluation for new targets and technologies relevant for synaptic plasticity, including neuronal cell culture, morphology analysis of dendrites and spines, and various molecular readouts such as immunofluorescence, calcium imaging/FLIPR, high-content confocal imaging, and multielectrode array.

• Evaluate target and technology feasibility, and compound efficacy in iPSC-derived cell models and primary culture, including assay development and optimization.

• Analyze, interpret, and present data, with the ability to clearly communicate results in written and oral formats; may need to incorporate data from other members in the Research team to interpret data.

• Maintain accurate and timely documentation of activities through meticulous lab notebook practices and contributions to reports.

• Collaborate closely with cross-functional teams and external groups to coordinate and drive complex studies.

Basic Qualifications:

• Bachelors or Masters degree in neuroscience, cellular/molecular biology, genetics, or related scientific field with 2+ years of relevant biotech, pharmaceutical, or academic work experience.

Additional Skills/Preferences:

• Experience with human iPSC co-culture system, CRISPR gene editing, viral vector use, and high-content imaging instruments

• Demonstrated ability to function as a member of an interdisciplinary team and contribute within a highly collaborative environment

• Exceptionally creative, organized, and detail-oriented

• Excellent communication skills, with the ability to thoroughly document, interpret, and effectively present scientific data to other scientists and non-scientists

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$69,000 - $179,300

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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