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Pfizer Global Medical Strategy Lead, Sr. Director (MD) in Cambridge, Massachusetts


Today, Pfizer Oncology has an industry-leading portfolio of 25 approved innovative cancer medicines, including major therapies for metastatic breast cancer, prostate cancer, urothelial carcinoma and haemato-oncological malignancies. Pfizer's in-line portfolio is focused on four broad, key areas: breast cancer, genitourinary cancer, hematology and precision medicine, complemented by an extensive pipeline of over 50 programs in clinical development.

  • Aligned to one or more asset programs in clinical development and/or in-line products, the Pfizer Oncology Global Medical Strategy Lead is a core member of the Global Product Team (GPT) and represents the Global Medical Strategy and the Medical Sub-Team (MST) at the GPT.

  • As the coordinator of the MST, this individual is responsible for providing strategic medical leadership for their program(s) as they progress through the development journey from clinical candidate through to commercialization.

  • A highly cross functional role, the incumbent will work in close collaboration with colleagues in Oncology Clinical Development, Oncology Medical Affairs Field Medical, International Medical Affairs, Pfizer U.S. (Medical Platforms), Safety, Oncology Regulatory Strategy, Global Value and Access (and other functions as needed) to co-develop holistic global medical strategy deliverables, including the Integrated Evidence Plan, Scientific Communications Platform, Medical Communications Plan and Scientific Engagement Plan.

  • Medical Strategy Leads are highly visible members of the Pfizer Oncology team to the external scientific community, as the interface between Key Opinion Leaders (KOL)s, Investigators and competitive insights from the scientific/medical community, as well as partner/collaborators for Clinical / R&D facing topics.

  • Internally, the role will act as an SME and ad-hoc participant in Development Review Committee discussions, Brand planning discussions and milestones endorsement meetings.


  • The role is responsible for integrated Medical Affairs representation on the GPT and as such is responsible for the end-to-end leadership of the asset/product, including translating cross-functional needs and external stakeholder insights into actionable research and medical deliverables.

  • Coordinates the Medical Sub-Team (MST). Responsible for facilitating meeting scheduling, agenda items, driving to decisions and meeting minutes with all key stakeholders. Responsible for representing output at the GPT. Individual functional leaders are accountable for leading their specific agenda topics.

  • At the GPT, responsible for delivering end-to-end medical leadership, translating cross functional needs and customer insights into actionable research and medical deliverables.

  • Responsible for collaborating globally with KOLs and scientific experts in support of Pfizer Oncology and clinical development / regional priorities through advisory boards, steering committees, 1:1 KOL interactions, and informing and adapting the R&D level program and deliverables in real time.

  • At phase 3 study reads outs (top line reports), responsible for crystallizing all the medical messaging from study read-outs, for internal and external use.

  • Responsible for working with MST members to build a bridge connecting R&D, commercial strategy and customer facing teams - avoiding functional silos.

  • As a subject matter expert, the incumbent will provide Medical, clinical landscape, and product expertise input into clinical development plans, trial designs, brand plans and other evidence generation plans that represents KOL/Investigator and competitive insights, with the intent to position the medicine for success in the future.

  • Working with other functions within Pfizer Oncology (including product Clinical Development Leads), responsible for external messaging from all R&D activities, including support for Investor Relations.

  • Establish deep connectivity with Clinical Trial Study teams to advance key deliverables end to end, from study concept through study data read out and closure., to support lightspeed clinical trial execution.

  • Collaborate with Clinical Development & Operations, Oncology Clinical Development Officer, Oncology Field Medical and International Medical Affairs on KOL/Investigator identification and site education and support.

  • Collaborate cross functionally with Oncology Field Medical and Pfizer U.S. (Medical Platforms) to prepare and drive scientific engagement plans to support trial awareness, site education, and recruitment initiatives.

  • Work with Field Medical and Worldwide Medical to enable where appropriate, early patient access through sanctioned programs where there are significant delays in market availability, and urgent unmet need as identified by regional / country teams.

  • Ensure the ISR Strategy is aligned with the clinical development plan, regulatory strategy and safety strategy. Participate in approval governance for proposed ISRs and CRCs

  • Establish the Scientific Communications Plan early in development based on target profile, clinical evidence, disease state / landscape, and aspirational label.

  • Responsible for working with MST members to build an overarching medical narrative and publication plan.

  • As part of the MST ensure country-specific Medical Education Plans remain in alignment with the Scientific Communications Platform, Clinical Development Plan and regulatory status, when appropriate.

  • Participate in cross-functional Congress Steering Committee to develop congress engagement plan and participation based on impact to R&D strategy and in-line products.

  • Pfizer representation on Partner/Collaborator governance committees related to Clinical / R&D / Medical facing topic (e.g., JDC, JSC, Joint Medical Affairs Working Groups with partners/Alliances)


  • MD or DO in a related medical field with extensive experience and strong understanding of biopharmaceutical drug development.

  • Oncology clinical development or Medical Affairs experience needed; relevant academic and clinical Oncology experience will be considered.

  • 10+ years of progressive experience in global medical affairs and/or clinical development in a pharmaceutical or biotech organization.

  • Strong experience and knowledge of the Oncology competitive landscape, stakeholder community and demonstrated deep expertise of their TA and medicines they are supporting.

  • Excellent interpersonal and communication skills.Ability to think strategicallywith a collaborative mindset and a proven track record of working effectively in diverse teams involving complex multi-functional disciplines.

  • A proven commitment to investing in and developing teams and individuals.

Location is hybrid - must be on site 2.5 days per week.


Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.