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KSQ Therapeutics Human Resources Generalist in Cambridge, Massachusetts

At KSQ Therapeutics, we seek to understand the role of every human gene in each disease, each tissue, and each cell that we study. This comprehensive approach has resulted in a massive, experimentally derived dataset that we have found to be remarkably predictive of past successes and failures in oncology and immuno-oncology product development. Utilizing this approach, we also identified a number of opportunities for the development of new medicines. As a result, we have aggressively invested in these distinct, highly validated pathways for new drug development with the expectation that the medicines we create may become the next breakthrough products for patients.

Founded in late 2015, KSQ is a preclinical-stage biotech in Kendall Square that has rapidly advanced the field of CRISPR-enabled functional genomics, from in vitro cell autonomous screens to more complex genome-scale screens of immune cells in vivo. The company has expanded the scope of its technology to include multiple cell types and to unlock areas beyond oncology. KSQ is led by a team of accomplished industry experts in drug discovery and development.

Position Summary:

KSQ Therapeutics, Inc. is seeking an exceptional, highly Human Resources Generalist to take on a wide range of HR tasks in support of the HR department’s operations and goals. The Human Resources Generalist will play a key role in the success of the organization by bringing their HR expertise to support the growing employee base. The successful candidate will demonstrate uncompromising integrity, confidentiality and have a strong work ethic.


Administer and manage benefits enrollments and materials

Assist in talent acquisition and recruitment process

Assist in new employee onboarding and orientation

Maintain physical and digital files for employees and their documents and benefits records

Ensure compliance with labor regulations

Organize mid-year and annual employee performance reviews

Assist in development and implementation of human resource policies

Assist in the organization and development of employee engagement activities

Design, promote, and implement HR programs and events

Covid-19 vaccination is a condition of employment at KSQ, subject to reasonable accommodation where required by law. Employees must be fully vaccinated by date of hire to be considered.


  • 4-6 years of experience as an HR Generalist required

  • Bachelor’s Degree in Human Resources, Business Administration or relevant field required

  • SHRM certification preferred

  • Excellent verbal, interpersonal, and written communication skills

  • Excellent organizational skills and attention to detail

  • Understanding of general human resources policies and procedures

  • Knowledge of employment/labor laws

  • Knowledge of MS Office; HRIS systems will be a plus

  • Aptitude in problem-solving

  • Desire to work as a team with a results-driven approach