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System One Scientist Cellular Genomics in Cambridge, Massachusetts

Job Title: Scientist Cellular Genomics

Location: Cambridge, MA

Type: Contract

Responsibilities

  • Follow existing lab standard operating procedures to:

  • Participate in sample collection of murine and human tissues, including the preparation of tubes, interfacing with in vivo scientists to retrieve samples, isolation of primary immune cells, and standard mammalian cell culture

  • Participate in sample preparation of murine and human tissues, including tissue fixation, dissociation, sectioning, and antibody staining

  • Generate spatial and single-cell data via a number of commercial workflows, including 10x Genomics and Parse Technologies

  • Interpret quality control metrics for spatial, single-cell and cytometry experiments

    Requirements

  • MA + 3 years of experience in Biology, Immunology, or a related field

  • 3+ years of hands-on experience with standard immunoprofiling technologies, including

  • Flow Cytometry

  • Single-cell library preparation (ideally 10x Genomics or Parse Technology)

  • Preparation and loading of Illumina sequencing libraries

  • Bonus: generation of spatial transcriptomics data (any technology)

  • 3+ years of experience with primary immune cells, including

  • Primary immune cell isolation

  • Maintenance of immune cell lines

  • Cell culture and in vitro stimulation of primary immune cells

  • Bonus: experience with CRISPR mediated functional genomics, including electroporation of primary immune cells

    Benefits

    System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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