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Actalent Senior Scientist in Cambridge, Massachusetts

See below to learn more about a Sr. Scientist opening with a rapidly growing cell therapy company!

Please contact naburns@actalentservices.com if you or someone you know if interested. You can also apply to this posting directly.

Department Description:

The Research and Development group supports the continuing development, characterization and validation of manufacturing methods, novel assays, new technology and operational improvements. This group manages technology transfers, clinical manufacturing, training, database development, trending analysis and stability. The R&D team plays an important role in commercial manufacturing troubleshooting, root cause investigation, process optimization and product life cycle management.

Position Summary: Applies scientific principles and expertise in the design and development of robust, cost-effective manufacturing procedures and associated analytical method that meet quality, GMP, regulatory and health, safety, and environmental standards.

Core Responsibilities:

  • Demonstrates a comprehensive solid understanding and use of scientific principles and professional practices, to solve a wide range of complex problems in creative and practical ways.

  • Leads cross-functional development teams and provides scientific support and guidance in the development, scale-up, optimization and operation of methods for the production and testing of new components, technologies and products.

  • Maintains and demonstrates significant knowledge of state-of-the art principles and theories in area of responsibility.

  • Independently reviews existing process and analytical development and production data; designs and conducts necessary experiments; interprets results; recommends changes or additional experiments.

  • Designs, executes, and interprets experiments to identify new methods to enhance the manufacture of or characterization of products in regards to safety, identity, strength, purity, stability and quality with minimal direction.

  • Stay abreast of new developments/technologies in areas of responsibility. Prepares proposals for introduction of technologies outlining the positive impact to the product for cost and/or quality.

  • Participate in establishing project strategy in consultation with management.

  • Represents the corporation in the greater biotech community by publishing in peer review journals and participation in scientific/technical conferences.

  • Represents the organization as the prime technical contact on contracts and projects. Interacts with external personnel on significant technical matters often requiring coordination between organizations.

  • Guides the successful completion of major programs and may function in a project leadership role.

  • Directs the work of more junior staff. Provides technical guidance and trains less experienced staff.

  • Other duties as assigned.

Skills:

assay development, GMP, Potency, PCR, ddpcr, rtpcr, qPCR, mammalian cell culture, cell culture, Biochemistry, cell banking, RNA Analysis, DNA Analysis, Assay, Molecular biology

Leadership qualifications include, among other requirements:

  • Understanding, observing, and adhering to the goals and policies outlined in company Code of Business Conduct and Ethics

  • Being honest and treating people with respect and courtesy.

  • Constantly striving to make the company a great place to work, and a company respected for the quality of its people and products.

  • Serving as role models for our fellow employees and business partners by acting responsibly, fairly, and honestly in our dealings and exercising sound judgment in performing our jobs.

Basic Qualifications:

  • BS and 10+ years of related work experience, or

  • MS and 8+ years of related work experience, or

  • Ph.D. or equivalent in Biology, Biochemistry, Biomedical engineering, Pharmaceutical Sciences or related fields and 6+ years of related work experience.

  • Advanced expertise in mammalian cell culture and related techniques.

  • Familiarity with technical writing and statistical analysis to produce research protocols and reports.

Preferred Qualifications:

  • Ph.D. preferred

  • 6+ years of experience working on development or support of assays and/or manufacturing processes for a biological drug in a GMP facility.

  • 6+ years of experience in isolation and culturing human primary cells.

  • Experience with medium development, cell banking methods and development of cell-based assays.

  • 2+ years of experience in developing autologous cell therapies or tissue engineered products.

  • Extensive hands-on experience in analytical methods for protein, RNA and DNA analysis.

  • Prior experience in cGMP environment and clean room requirements.

  • Prior success with cell-based assay development.

  • Good leadership and people skills, team work experience, and demonstrated conflict handling and resolution ability and negotiation skills.

  • Good achievement and record in scientific research and technical development as evidenced by research paper, conference presentation, and patent publications.

  • Self-motivated, organized

Experience Level:

Expert Level

About Actalent:

Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We’re supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions.

The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

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