Massachusetts Veterans Jobs

Genomic Medicine Purification Process Development Post Doctoral Fellow, Waltham, MA

About the job

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Position Overview/Department Description:

The Genomic Medicine Unit (GMU) Chemistry, Manufacturing and Control (CMC) group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support the development of life-changing advanced gene therapy products, including recombinant Adeno-associated viral vectors (AAV) and non-viral gene therapy products. We are seeking a highly motivated and creative scientist to join the Purification Process Development team as a Postdoctoral Fellow. This position focuses on advancing the application of machine learning to facilitate anion exchange (AEX) chromatography for full vector enrichment in AAV drug substance process development. Additionally, the fellow will have significant opportunities to contribute to Sanofi's digital transformation by collaborating on projects with other CMC teams and global process modeling and data science teams.

This is an exciting opportunity to leverage the transformative power of data science in the CMC field, accelerating breakthroughs for patients. Join us and contribute to Sanofi's ambition to become the first pharmaceutical company powered by artificial intelligence at scale.

Key Responsibilities:

• Systematically collect, clean, and analyze AEX chromatography data to enable advanced data analysis.

• Build and evaluate predictive machine learning models.

• Integrate predictive machine learning models with the chromatography system to enable real-time decision-making.

• Collaborate with cross-functional teams and present scientific findings.

• Draft technical reports and external publications to summarize scientific findings.

Basic Qualifications:

• Currently holding a Ph.D. in chemical engineering, bioinformatics, cheminformatics, or data science with a strong track record of publications.

• Must be able to relocate to our Waltham, MA office location and work 40hrs.week for the full duration of the Postdoc Fellow Program

• Must have permanent US work authorization

• Strong laboratory experience and technical expertise in chromatography

• Knowledge and hands-on experience with machine learning methodologies.

• Proficiency in programming languages such as Python or R for data analysis and model building.

• Ability to work independently or with minimal supervision and collaborate in a highly matrixed environment.

• Be effective for both verbal and written communications.

• Highly motivated and can deliver results within defined time frame.

• Curious and bold in proposing creative experimental designs and ideas.

• Ability to work in Biosafety Level 2 (BSL-2) lab, follow safe lab procedures, and maintain good laboratory practices including detail-oriented laboratory notebook documentation.

Preferred Qualifications:

• Understanding of manufacturing scale purification process to produce drug substance.

• Experience in mechanistic modeling and data-driven models in purification process development.

• Demonstrated ability to translate mathematical models into computer programs using programming languages, e.g. Python or similar.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team.​​

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.​​

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.​​

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.​

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.​

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